After David attempted to commit suicide, he was admitted to Clockworks to treat his schizophrenia. It was there that he befriended Lenny Busker and fell in love with Sydney Barrett, a mutant whose uncontrollable powers has made her isolate herself from physical contact. Their romantic relationship is cut short when Sydney reveals that she is about to leave Clockworks, causing David to kiss her as she is about to depart. This triggers Sydney's mutation and the two switch bodies. In David's body, Sydney finds herself unable to control his vast psychic abilities, causing her to inadvertently transport all the patients at Clockworks into their rooms and making the doors disappear. Lenny is killed in the process, her corpse partially phased through the walls. In Sydney's body, David is told to leave immediately by the former's psychiatrist. Before doing so, he sees Melanie Bird and her mutant team arrive, though his memories of the day are altered to believe that it was in fact Clark of Division 3 .
- Clockworks is named after Stanley Kubrick's A Clockwork Orange, which Legion creator Noah Hawley has admitted is an inspiration for the show .
- The different colored uniforms worn by Clockworks Psychiatric Hospital patients are to classify a patient's level of risk of violence. Patients who wear white uniforms are of no risk of violence, yellow uniforms have a mild to moderate risk of violence, and red uniforms are of a high risk of violence.